Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502778 | 1.00 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL2511788 | 0.94 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL2505590 | 0.94 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL2508185 | 0.93 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL2503861 | 0.93 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL2501693 | 0.93 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL2505626 | 0.93 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL2498052 | 0.92 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL2508142 | 0.92 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL2500818 | 0.91 | KCNH2 (0.57) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376497-A1 | 5-AMINO-2-(1-HYDROXY-ETHYL)-TETRAHYDROPYRAN DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010067332-A1 | 5-AMINO-2-(1-HYDROXY-ETHYL)-TETRAHYDROPYRAN DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-17 | — | — | WO | disclosed |