SCHEMBL25091045

SCHEMBL25091045

C[C@H](N)CCC[C@H]1CCOC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TLR7 Q9NYK1 2/20 0.32
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27358191 0.78
SCHEMBL1678720 0.78
SCHEMBL766688 0.76 PIK3CD (0.39) TLR7DRD4
SCHEMBL16997066 0.76 PIK3CD (0.39) TLR7DRD4
SCHEMBL30837730 0.76 PIK3CD (0.35) OPRM1
SCHEMBL25660581 0.76 GSR (0.42)
SCHEMBL5061598 0.74
SCHEMBL24224169 0.74 CYP1A2 (0.43) OPRM1ALDH1A1TDP1
SCHEMBL21572829 0.74 CYP1A2 (0.43) OPRM1ALDH1A1TDP1
SCHEMBL5673317 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 OPRM1 4831/4885ALDH1A1 4303/4885TDP1 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.