Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 7/20 | 0.36 |
| ▸ | VHL | P40337 | 3/20 | 0.34 |
| ▸ | ELOC | Q15369 | 2/20 | 0.34 |
| ▸ | ELOB | Q15370 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP4 | P49662 | 1/20 | 0.31 |
| ▸ | CASP5 | P51878 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757232 | 0.88 | STAT6 (0.36) | STAT6VHLELOCELOBELANE | |
| SCHEMBL25757826 | 0.88 | VHL (0.37) | STAT6VHLELOCELOBELANE | |
| SCHEMBL24068380 | 0.88 | STAT6 (0.36) | STAT6VHLELOCELOBELANE | |
| SCHEMBL25906673 | 0.82 | EPHX1 (0.37) | — | |
| SCHEMBL26749959 | 0.81 | STAT6 (0.38) | STAT6ELANEDPP4DPP8DPP9 | |
| SCHEMBL12811967 | 0.80 | STAT6 (0.38) | STAT6ELANEDPP4DPP8DPP9 | |
| SCHEMBL24068280 | 0.79 | VHL (0.35) | STAT6VHLELOCELOBELANE | |
| SCHEMBL21696763 | 0.79 | STAT6 (0.43) | STAT6ELANEDPP4DPP8DPP9 | |
| SCHEMBL25885362 | 0.79 | STAT6 (0.43) | STAT6ELANEDPP4DPP8DPP9 | |
| SCHEMBL24068291 | 0.78 | VHL (0.37) | VHLELOCELOBELANEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230070613-A1 | PROTEIN TYROSINE KINASE 6 (PTK6) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230070613-A1 | PROTEIN TYROSINE KINASE 6 (PTK6) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE | PTK6, NEK6, GRK6 | STAT6 3093/4885VHL 639/4885ELOC 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.