⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624371 | 0.88 | — | — | |
| SCHEMBL18649665 | 0.86 | — | — | |
| SCHEMBL24415189 | 0.83 | — | — | |
| SCHEMBL5667895 | 0.83 | CYP2D6 (0.32) | — | |
| SCHEMBL25587421 | 0.82 | CHRM2 (0.31) | — | |
| SCHEMBL9640729 | 0.78 | CHRM2 (0.38) | — | |
| SCHEMBL15932260 | 0.73 | CHRM2 (0.46) | — | |
| SCHEMBL14272015 | 0.73 | — | — | |
| SCHEMBL19241438 | 0.71 | — | — | |
| SCHEMBL10108794 | 0.71 | CYP2C19 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230070613-A1 | PROTEIN TYROSINE KINASE 6 (PTK6) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-03-09 | — | — | US | disclosed |