Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20690443 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL21480134 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL12357446 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL17572004 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL14110948 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL25375910 | 0.71 | CHRM2 (0.33) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL23245840 | 0.71 | CHRM2 (0.55) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL23245486 | 0.71 | CHRM2 (0.55) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL18403419 | 0.71 | CHRM2 (0.55) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL15810876 | 0.71 | CHRM2 (0.55) | SMN1; SMN2CHRM2CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660023-B1 | THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2023-03-08 | — | — | EP | disclosed |