Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918822 | 0.74 | POLB (1.00) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL15314289 | 0.74 | POLB (1.00) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL12408155 | 0.71 | POLB (0.96) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL27290865 | 0.69 | POLB (0.59) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL27290941 | 0.69 | POLB (0.59) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL14204046 | 0.69 | POLB (0.59) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL11914610 | 0.69 | POLB (0.58) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL14048244 | 0.69 | POLB (0.58) | POLBHPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL22485313 | 0.69 | POLB (0.58) | POLBHPGDALDH1A1HTTKDM4E | |
| SCHEMBL22484889 | 0.69 | POLB (0.58) | POLBHPGDALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |