Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | LCP2 | Q13094 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30233742 | 1.00 | MAP4K1 (0.36) | MAP4K1PIK3CAMTORRPS6KA2PRKD2 | |
| SCHEMBL29261275 | 0.85 | MAP4K1 (0.37) | MAP4K1RPS6KA2PRKD2LCP2 | |
| SCHEMBL30233476 | 0.82 | TLR9 (0.41) | PIK3CAMTOR | |
| SCHEMBL30913170 | 0.82 | TLR9 (0.41) | PIK3CAMTOR | |
| SCHEMBL30543372 | 0.82 | HSP90AA1 (0.37) | PIK3CAMTORPIM1PIM2 | |
| SCHEMBL29222584 | 0.82 | HSP90AA1 (0.37) | PIK3CAMTORPIM1PIM2 | |
| SCHEMBL30913133 | 0.79 | JAK1 (0.39) | MAP4K1PIK3CAMTOR | |
| SCHEMBL30232843 | 0.79 | JAK1 (0.39) | MAP4K1PIK3CAMTOR | |
| SCHEMBL29261279 | 0.79 | TLR9 (0.40) | PIK3CA | |
| SCHEMBL30233026 | 0.76 | JAK1 (0.38) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103369-A | Pyridolactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |