Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515806 | 0.94 | GCK (0.62) | GCK | |
| SCHEMBL2512504 | 0.88 | GCK (0.68) | GCK | |
| SCHEMBL2515235 | 0.85 | GCK (0.75) | GCK | |
| SCHEMBL2513851 | 0.85 | GCK (0.70) | GCK | |
| SCHEMBL2513450 | 0.84 | GCK (0.60) | GCK | |
| SCHEMBL2518716 | 0.82 | GCK (0.68) | GCK | |
| SCHEMBL2514932 | 0.82 | GCK (0.60) | GCK | |
| SCHEMBL2514574 | 0.82 | GCK (0.68) | GCK | |
| SCHEMBL2669022 | 0.81 | GCK (0.67) | GCK | |
| SCHEMBL2517337 | 0.81 | GCK (0.67) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034822-B2 | Glucokinase activators | TAKEDA SAN DIEGO, INC. (US) | 2011-10-11 | — | — | US | claimed |