SCHEMBL2510457

SCHEMBL2510457

CC(=O)C(O)[C@H]1O[C@@H](Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.72
RPS6KA3 P51812 6/20 0.69
CYP3A4 P08684 6/20 0.67
P4HB P07237 4/20 0.67
AKR1B1 P15121 3/20 0.67
CA12 O43570 2/20 0.67
CA2 P00918 2/20 0.67
CA4 P22748 2/20 0.67
CA7 P43166 2/20 0.67
ACHE P22303 1/20 0.67
CYP2D6 P10635 1/20 0.65
RPS6KA1 Q15418 1/20 0.65
SLCO2B1 O94956 2/20 0.62
MAOA P21397 2/20 0.62
EPHX2 P34913 2/20 0.62
XDH P47989 2/20 0.62
PIM2 Q9P1W9 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
KDM4E B2RXH2 1/20 0.62
ALDH1A1 P00352 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17938818 0.93 KDM4E (0.73) CYP3A4P4HBAKR1B1CA12CA2
SCHEMBL7601750 0.93 KDM4E (0.73) CYP3A4P4HBAKR1B1CA12CA2
SCHEMBL2510346 0.93 KDM4E (0.73) CYP3A4P4HBAKR1B1CA12CA2
SCHEMBL2007120 0.88 NQO2 (0.65) NQO2RPS6KA3CYP3A4P4HBAKR1B1
SCHEMBL1278982 0.87 CYP3A4 (0.69) NQO2RPS6KA3CYP3A4P4HBAKR1B1
SCHEMBL18670353 0.87 CYP3A4 (0.69) NQO2RPS6KA3CYP3A4P4HBAKR1B1
SCHEMBL1287866 0.87 CYP3A4 (0.69) NQO2RPS6KA3CYP3A4P4HBAKR1B1
SCHEMBL9992609 0.87 CYP3A4 (0.69) NQO2RPS6KA3CYP3A4P4HBAKR1B1
SCHEMBL6903921 0.86 NQO2 (0.70) NQO2RPS6KA3CYP3A4P4HBAKR1B1
Afzelin SCHEMBL1689477 0.84 NQO2 (1.00) NQO2RPS6KA3CYP3A4P4HBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110244521-A1 METHOD FOR PREPARATION OF RECOBINANT DNA NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2011-10-06 US disclosed
EP-2202313-A1 METHOD FOR PREPARATION OF RECOMBINANT DNA National University Corporation Hokkaido University (JP) 2010-06-30 EP disclosed