Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612907 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL7994870 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL9810824 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL6465598 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL5704108 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL15821144 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL12230908 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL2511095 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL6465596 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E | |
| SCHEMBL17010736 | 1.00 | AKT1 (0.48) | AKT1CETPTLR4SYNJ2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46955-E1 | Sulfated oligosaccharide derivatives | PROGEN PG500 SERIES PTY LTD (AU) | 2018-07-17 | — | — | US | disclosed |
| EP-2205616-B1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LTD (AU) | 2016-04-27 | — | — | EP | disclosed |
| US-8828952-B2 | Sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LIMITED (AU) | 2014-09-09 | — | — | US | disclosed |
| US-20110245196-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PG500 SERIES PTY LTD (AU) | 2011-10-06 | — | — | US | disclosed |
| EP-2205616-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | Progen Pharmaceuticals Limited (AU) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009049370-A1 | NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2009-04-23 | — | — | WO | disclosed |