Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25117920 | 1.00 | JAK2 (0.36) | JAK2NTRK1KDM4EHPGDHSD17B10 | |
| SCHEMBL25117793 | 0.93 | JAK2 (0.35) | JAK2NTRK1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL25117959 | 0.92 | CCNA2 (0.37) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25117961 | 0.92 | CCNA2 (0.37) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118011 | 0.90 | MKNK2 (0.35) | JAK2NTRK1KDM4EHPGDHSD17B10 | |
| SCHEMBL25117792 | 0.89 | JAK2 (0.35) | JAK2NTRK1KDM4EHPGDHSD17B10 | |
| SCHEMBL25839398 | 0.89 | JAK2 (0.36) | JAK2NTRK1KDM4EHPGDHSD17B10 | |
| SCHEMBL25118125 | 0.88 | JAK3 (0.32) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118122 | 0.88 | JAK3 (0.32) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25839410 | 0.87 | JAK2 (0.34) | JAK2NTRK1ADORA3ADORA2AMKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4163283-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-04-12 | — | — | EP | disclosed |