Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 10/20 | 0.75 |
| ▸ | STK3 | Q13188 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 5/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.42 |
| ▸ | PLK2 | Q9NYY3 | 3/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060508 | 0.99 | STK4 (0.75) | STK4STK3PSEN1PSEN2APH1B | |
| SCHEMBL24928824 | 0.87 | STK4 (0.76) | STK4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23998718 | 0.86 | STK4 (1.00) | STK4STK3PLK1PLK3PLK2 | |
| SCHEMBL25060520 | 0.85 | STK4 (0.75) | STK4STK3PSEN1PSEN2APH1B | |
| SCHEMBL23998712 | 0.85 | STK4 (1.00) | STK4STK3PLK1PLK3PLK2 | |
| SCHEMBL23998720 | 0.83 | STK4 (1.00) | STK4STK3PLK1PLK3PLK2 | |
| SCHEMBL25060523 | 0.82 | STK4 (0.74) | STK4STK3PSEN1PSEN2APH1B | |
| SCHEMBL23998724 | 0.80 | STK4 (1.00) | STK4STK3PLK1PLK3PLK2 | |
| SCHEMBL25060514 | 0.80 | STK4 (0.73) | STK4STK3PSEN1PSEN2APH1B | |
| SCHEMBL25060581 | 0.78 | STK4 (0.71) | STK4STK3MAPK7PIK3CDAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159845-A1 | CULTURE MEDIUM FOR LARYNGEAL CANCER EPITHELIAL CELLS, CULTURE METHOD, AND APPLICATION THEREOF | CAS (Hefei) Institute of Technology Innovation (CN) | 2023-04-05 | — | — | EP | disclosed |