Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785104 | 0.86 | PTPN11 (0.70) | PTPN11 | |
| SCHEMBL20415582 | 0.82 | PTPN11 (0.79) | PTPN11 | |
| SCHEMBL25124240 | 0.81 | PTPN11 (0.53) | PTPN11 | |
| SCHEMBL20909300 | 0.79 | PTPN11 (0.71) | PTPN11 | |
| SCHEMBL20415622 | 0.79 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL27368979 | 0.78 | PTPN11 (0.51) | PTPN11 | |
| SCHEMBL23562076 | 0.77 | PTPN11 (0.52) | PTPN11 | |
| SCHEMBL19785525 | 0.76 | PTPN11 (0.57) | PTPN11 | |
| SCHEMBL19785527 | 0.76 | PTPN11 (0.57) | PTPN11 | |
| SCHEMBL21154439 | 0.76 | PTPN11 (0.59) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3571189-B1 | PYRIDINE COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS | REVOLUTION MEDICINES INC (US) | 2023-03-29 | — | — | EP | disclosed |