Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404981 | 0.84 | HSD17B3 (0.64) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL24201501 | 0.82 | HSD17B3 (0.67) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL19014017 | 0.81 | HSD17B3 (0.60) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL23476592 | 0.80 | TSHR (0.41) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL22102183 | 0.79 | HSD17B3 (0.71) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL24385889 | 0.79 | HSD17B3 (0.61) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL24386318 | 0.79 | MAPT (0.58) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL29311982 | 0.78 | HSD17B3 (0.60) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL27273811 | 0.78 | HSD17B3 (0.60) | HSD17B3TSHRNOTUMMAPTMEN1 | |
| SCHEMBL19287152 | 0.77 | MAPT (0.78) | TSHRNOTUMMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023047090-A1 | ANTIBODY-DRUG CONJUGATES | SPIREA LIMITED (GB) | 2023-03-30 | — | — | WO | disclosed |