Adenosine Phosphate

Adenosine Phosphate

SCHEMBL2512522

NP(=O)(O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 5/20 0.96
P2RY2 P41231 3/20 0.96
SRC P12931 2/20 0.96
SMN1; SMN2 Q16637 2/20 0.96
TRPM2 O94759 2/20 0.96
TAS1R3 Q7RTX0 2/20 0.96
TAS1R1 Q7RTX1 2/20 0.96
DNPH1 O43598 1/20 0.96
PRKAB2 O43741 1/20 0.96
LDHA P00338 1/20 0.96
ADRB2 P07550 1/20 0.96
FBP1 P09467 1/20 0.96
ADORA1 P30542 1/20 0.96
PRKAG1 P54619 1/20 0.96
PRKAA2 P54646 1/20 0.96
PDE4D Q08499 1/20 0.96
KCNH2 Q12809 1/20 0.96
PRKAA1 Q13131 1/20 0.96
PDE3A Q14432 1/20 0.96
P2RY11 Q96G91 1/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Phosphate SCHEMBL13374692 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL144997 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL11977309 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL20277555 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL1338615 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL19420134 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL13170051 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL8572634 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL132458 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL14478782 0.98 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9169507-B2 Modified RNA ligase for efficient 3′ modification of RNA THE ROCKEFELLER UNIVERSITY (US) 2015-10-27 US disclosed
US-20150010950-A1 Modified RNA Ligase for Efficient 3' Modification of RNA UNIV ROCKEFELLER (US) 2015-01-08 US disclosed
US-8809022-B2 Modified RNA ligase for efficient 3′ modification of RNA THE ROCKEFELLER UNIVERSITY (US) 2014-08-19 US disclosed
US-20130130322-A1 Modified RNA Ligase for Efficient 3` Modification of RNA THE ROCKEFELLER UNIVERSITY (US) 2013-05-23 US disclosed
US-8383370-B2 Modified RNA ligase for efficient 3′ modification of RNA THE ROCKEFELLER UNIVERSITY (US) 2013-02-26 US disclosed
US-20110244523-A1 Modified RNA Ligase for Efficient 3` Modification of RNA THE ROCKEFELLER UNIVERSITY (US) 2011-10-06 US disclosed
WO-2008094599-A2 MODIFIED RNA LIGASE FOR EFFICIENT 3' MODIFICATION OF RNA ROCKEFELLER UNIVERSITY, THE (US) 2008-08-07 WO disclosed