Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 15/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413104 | 0.87 | CYP17A1 (0.45) | CYP17A1 | |
| SCHEMBL4889660 | 0.84 | CDK8 (0.67) | CDK8 | |
| SCHEMBL30435041 | 0.83 | CDK8 (0.48) | CDK8SYK | |
| SCHEMBL25129021 | 0.82 | CDK8 (0.47) | CDK8SIRT2SYKCYP17A1TDP2 | |
| SCHEMBL25129016 | 0.82 | CDK8 (0.47) | CDK8SYKCYP17A1TDP2 | |
| SCHEMBL29850092 | 0.82 | NAMPT (0.49) | CYP17A1 | |
| SCHEMBL853159 | 0.82 | NAMPT (0.49) | CYP17A1 | |
| SCHEMBL4732688 | 0.81 | CDK8 (0.46) | CDK8SYK | |
| SCHEMBL29996697 | 0.81 | CDK8 (0.46) | CDK8SYK | |
| SCHEMBL4880831 | 0.79 | HTT (0.51) | CDK8ALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040793-A1 | ANTI-INFLAMMATORY COMPOUND AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2023-03-23 | — | — | WO | disclosed |