Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.80 |
| ▸ | DPP8 | Q6V1X1 | 14/20 | 0.80 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667452 | 0.84 | DPP4 (0.84) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL2667530 | 0.82 | DPP4 (0.77) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL16230987 | 0.80 | DPP4 (0.83) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL16231055 | 0.80 | DPP4 (0.83) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL6877160 | 0.80 | DPP4 (0.83) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL1071184 | 0.80 | DPP4 (0.98) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL7902672 | 0.79 | DPP4 (0.78) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL6853393 | 0.79 | DPP4 (0.78) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL14267898 | 0.79 | DPP4 (0.78) | DPP4DPP8DPP7DPP9ACE | |
| Hydrochloric Acid SCHEMBL6915483 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103175-A1 | TRANSAMINASE MUTANT, IMMOBILIZED TRANSAMINASE AND USE IN PREPARATION OF SITAGLIPTIN | ABIOCHEM BIOTECHNOLOGY CO, LTD. (CN) | 2023-03-30 | — | — | US | disclosed |