Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513018 | 1.00 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2513017 | 1.00 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2513016 | 1.00 | GSK3B (0.55) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2488133 | 0.91 | GSK3B (0.53) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2488135 | 0.91 | GSK3B (0.53) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL14302424 | 0.91 | GSK3B (0.53) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2488137 | 0.91 | GSK3B (0.53) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2490764 | 0.89 | GSK3B (0.61) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2490762 | 0.89 | GSK3B (0.61) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL2490759 | 0.89 | GSK3B (0.61) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057141-B1 | PYRIMIDONE COMPOUNDS AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2011-10-26 | — | — | EP | disclosed |