Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ADH1B | P00325 | 3/20 | 0.44 |
| ▸ | ADH1A | P07327 | 3/20 | 0.44 |
| ▸ | ADH7 | P40394 | 3/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308857 | 0.87 | EPHX2 (0.39) | EPHX2ADH1BADH1AADH7ADH1C | |
| SCHEMBL28924668 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL20450540 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL28587326 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL3914424 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL14482719 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL3251209 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL14482131 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL2380206 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA | |
| SCHEMBL30661131 | 0.82 | EPHX2 (0.49) | EPHX2TDP1HDAC8ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |