⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280182 | 0.80 | — | — | |
| SCHEMBL24778654 | 0.80 | CYP19A1 (0.30) | — | |
| SCHEMBL25133855 | 0.72 | GBA1 (0.33) | — | |
| SCHEMBL31368061 | 0.71 | GBA1 (0.35) | — | |
| SCHEMBL22849322 | 0.69 | NR1H2 (0.56) | — | |
| SCHEMBL21998102 | 0.69 | NR1H2 (0.56) | — | |
| SCHEMBL1316560 | 0.66 | ESR2 (0.46) | — | |
| SCHEMBL130642 | 0.66 | ESR2 (0.46) | — | |
| SCHEMBL27912 | 0.66 | ESR2 (0.46) | — | |
| SCHEMBL2267415 | 0.66 | ESR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230097358-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2023-03-30 | — | — | US | disclosed |