Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | PTGFR | P43088 | 3/20 | 0.72 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.72 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.72 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.72 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.60 |
| ▸ | PTGIR | P43119 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prostaglandin H2 SCHEMBL25710166 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL25608059 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL13905974 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL14141363 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL13659008 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL24726791 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL12928438 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL13649343 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL21845800 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 | |
| Prostaglandin H2 SCHEMBL12141851 | 1.00 | TBXA2R (0.78) | TBXA2RLMNAALDH1A1PTGFRPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |