Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182719 | 1.00 | KDM1A (0.56) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL30212203 | 0.90 | KDM1A (0.50) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL25741446 | 0.88 | BTK (0.58) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL29126597 | 0.88 | EPHX2 (0.48) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL24078617 | 0.88 | EPHX2 (0.48) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL2647959 | 0.87 | KDM1A (0.62) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23951807 | 0.87 | KDM1A (0.48) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL14647010 | 0.87 | KDM1A (0.62) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23951710 | 0.86 | KDM1A (0.47) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL21996735 | 0.86 | KDM1A (0.45) | KDM1AMAOBKMT2AL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | KDM1A 1511/4885MAOB 1380/4885KMT2A 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.