Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.54 |
| ▸ | INSR | P06213 | 5/20 | 0.43 |
| ▸ | IGF1R | P08069 | 5/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26383426 | 0.94 | EGFR (0.55) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26385266 | 0.93 | EGFR (0.54) | EGFRINSRIGF1RALK | |
| SCHEMBL26403769 | 0.93 | EGFR (0.57) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26383312 | 0.92 | EGFR (0.63) | EGFR | |
| SCHEMBL26399217 | 0.92 | EGFR (0.54) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26387453 | 0.92 | EGFR (0.53) | EGFRINSRIGF1RALKMET | |
| SCHEMBL26403955 | 0.92 | EGFR (0.55) | EGFRINSRIGF1RALK | |
| SCHEMBL26403508 | 0.92 | EGFR (0.53) | EGFRINSRIGF1RALKMET | |
| SCHEMBL25791794 | 0.92 | EGFR (0.55) | EGFRINSRIGF1RALK | |
| SCHEMBL25789270 | 0.91 | EGFR (0.52) | EGFRINSRIGF1RALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-07-06 | — | — | US | disclosed |
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE1, EGFR, WEE2 | EGFR 2/4885INSR 284/4885IGF1R 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.