Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.51 |
| ▸ | INSR | P06213 | 4/20 | 0.51 |
| ▸ | IGF1R | P08069 | 3/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 2/20 | 0.51 |
| ▸ | GAK | O14976 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | STK10 | O94804 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | FYN | P06241 | 2/20 | 0.51 |
| ▸ | FES | P07332 | 2/20 | 0.51 |
| ▸ | YES1 | P07947 | 2/20 | 0.51 |
| ▸ | HCK | P08631 | 2/20 | 0.51 |
| ▸ | ROS1 | P08922 | 2/20 | 0.51 |
| ▸ | FER | P16591 | 2/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.51 |
| ▸ | LTK | P29376 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25144599 | 0.92 | EGFR (0.65) | EGFRALKINSRIGF1RBMPR1B | |
| SCHEMBL25144536 | 0.89 | ALK (0.64) | EGFRALKINSRIGF1RBMPR1B | |
| SCHEMBL25791461 | 0.88 | EGFR (0.56) | EGFRALKINSRIGF1R | |
| SCHEMBL25791867 | 0.88 | EGFR (0.56) | EGFRALKINSRIGF1R | |
| SCHEMBL25144784 | 0.88 | EGFR (0.56) | EGFRALKINSRIGF1RMET | |
| SCHEMBL25789078 | 0.87 | EGFR (0.56) | EGFRALKINSRIGF1R | |
| SCHEMBL25789194 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL25144597 | 0.87 | EGFR (0.57) | EGFRALKINSRIGF1R | |
| SCHEMBL25144473 | 0.86 | EGFR (0.57) | EGFRALKINSRIGF1R | |
| SCHEMBL25789063 | 0.86 | EGFR (0.61) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | disclosed |