Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30325275 | 0.84 | PADI4 (0.52) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL25145104 | 0.84 | PADI4 (0.52) | PTGER4PADI4CA12CA9MAPK1 | |
| Hydrochloric Acid SCHEMBL30325573 | 0.83 | PADI4 (0.53) | PTGER4PADI4CA12CA9MAPK1 | |
| Hydrochloric Acid SCHEMBL28524626 | 0.83 | PADI4 (0.53) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL25145034 | 0.83 | PADI4 (0.51) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL18247513 | 0.83 | PADI4 (0.51) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL25145044 | 0.82 | PADI4 (0.45) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL18247704 | 0.82 | PADI4 (0.49) | PTGER4PADI4CA12CA9KDM4E | |
| Lithium SCHEMBL18247699 | 0.82 | PADI4 (0.50) | PTGER4PADI4CA12CA9MAPK1 | |
| SCHEMBL18247694 | 0.82 | PADI4 (0.50) | PTGER4PADI4CA12CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |