SCHEMBL25145361

SCHEMBL25145361

CC1(C)c2ccccc2-c2c(N(c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)c3ccc4c(c3)oc3ccccc34)cccc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 2/20 0.32
AHR P35869 2/20 0.32
PGR P06401 1/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19168617 0.96 ALK (0.34) ALKAHRPGRMEN1MAPT
SCHEMBL24078285 0.96 ALK (0.34) ALKAHRPGRMEN1MAPT
SCHEMBL25145421 0.95 ALK (0.35) ALKAHRPGRMEN1MAPT
SCHEMBL25145352 0.94 ALK (0.32) ALK
SCHEMBL25145444 0.94 ALK (0.34) ALKAHRPGRMEN1MAPT
SCHEMBL25145494 0.94 AHR (0.34) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL24647662 0.93 ALK (0.32) ALK
SCHEMBL17637184 0.92 AHR (0.36) ALKAHRPGRMEN1MAPT
SCHEMBL21141228 0.91 AHR (0.34) ALKAHRPGRMEN1MAPT
SCHEMBL21094688 0.91 ALK (0.32) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146354-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ORGANIC COMPOUND, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-05-11 US disclosed
US-20230146354-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ORGANIC COMPOUND, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-05-11 US disclosed
US-20230124044-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-04-20 US disclosed