Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514433 | 1.00 | GCK (1.00) | GCK | |
| SCHEMBL2514668 | 0.88 | GCK (0.78) | GCK | |
| SCHEMBL2511322 | 0.88 | GCK (1.00) | GCK | |
| SCHEMBL2516375 | 0.88 | GCK (1.00) | GCK | |
| SCHEMBL2514859 | 0.88 | GCK (0.87) | GCK | |
| SCHEMBL2514553 | 0.87 | GCK (0.77) | GCK | |
| SCHEMBL2514588 | 0.87 | GCK (0.77) | GCK | |
| SCHEMBL2512605 | 0.86 | GCK (0.81) | GCK | |
| SCHEMBL2512764 | 0.86 | GCK (0.81) | GCK | |
| SCHEMBL2513843 | 0.86 | GCK (0.75) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034822-B2 | Glucokinase activators | TAKEDA SAN DIEGO, INC. (US) | 2011-10-11 | — | — | US | disclosed |