Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 17/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162066 | 0.90 | CTSC (0.60) | CTSCCTSKKCNH2CTSS | |
| SCHEMBL30194946 | 0.90 | CTSC (0.60) | CTSCCTSKKCNH2CTSS | |
| SCHEMBL16940311 | 0.90 | CTSC (0.60) | CTSCCTSKKCNH2CTSS | |
| SCHEMBL25371156 | 0.86 | CTSC (0.63) | CTSCCTSKCTSS | |
| SCHEMBL24981973 | 0.86 | CTSC (0.63) | CTSCCTSKCTSS | |
| SCHEMBL24981071 | 0.84 | CTSC (0.53) | CTSCCTSKCTSS | |
| SCHEMBL28989356 | 0.84 | CTSC (0.53) | CTSCCTSKCTSS | |
| SCHEMBL29455311 | 0.84 | CTSC (0.53) | CTSCCTSKCTSS | |
| SCHEMBL30738891 | 0.84 | CTSC (0.54) | CTSCCTSKKCNH2CTSS | |
| SCHEMBL24981828 | 0.83 | CTSC (0.57) | CTSCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-11-07 | — | — | US | disclosed |
| US-20230121807-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | HAISCO PHARMACEUTICALS PTE. LTD (SG) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | DPP4, DPP3, DPP9 | CTSC 4/4885CTSK 454/4885KCNH2 4526/4885 |
| US-20230121807-A1 | NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF | DPP4, DPP3, DPP9 | CTSC 4/4885CTSK 454/4885KCNH2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.