⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL2885785 | 0.85 | — | — | |
| Pyrrole SCHEMBL841068 | 0.85 | — | — | |
| Pyrrole SCHEMBL14840876 | 0.85 | — | — | |
| Pyrrole SCHEMBL15757584 | 0.85 | — | — | |
| Pyrrole SCHEMBL292 | 0.85 | — | — | |
| Pyrrole SCHEMBL27535135 | 0.85 | — | — | |
| Pyrrole SCHEMBL15801170 | 0.85 | — | — | |
| Pyrrole SCHEMBL28240403 | 0.82 | — | — | |
| Pyrrole SCHEMBL22748023 | 0.82 | — | — | |
| Pyrrole SCHEMBL28102631 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748601-B2 | Selective serine/threonine kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-10 | — | — | US | disclosed |
| US-8034821-B2 | Selective serine/threonine kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-10-11 | — | — | US | disclosed |
| US-20100256171-A1 | SELECTIVE SERINE/THREONINE KINASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-07 | — | — | US | disclosed |
| US-7687506-B2 | Selective serine/threonine kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-20090221614-A1 | SELECTIVE SERINE/THREONINE KINASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (CA) | 2009-09-03 | — | — | US | disclosed |
| US-20070082884-A1 | Selective serine/threonine kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-04-12 | — | — | US | disclosed |
| WO-2007038613-A2 | SELECTIVE SERINE/THREONINE KINASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-1185402-B1 | AZOLE/AMINE OXIDE WOOD PRESERVATIVES AND FUNGICIDES | LONZA AG (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2005000197-A2 | SELECTIVE SERINE/THREONINE KINASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-06 | — | — | WO | disclosed |
| US-6527981-B1 | Azole/amine oxide preservatives | LONZA INC. | 2003-03-04 | — | — | US | disclosed |
| EP-1185402-A1 | AZOLE/AMINE OXIDE WOOD PRESERVATIVES | LONZA INC. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000071314-A1 | AZOLE/AMINE OXIDE WOOD PRESERVATIVES | LONZA INC. (US) | 2000-11-30 | — | — | WO | disclosed |