Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 8/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20858757 | 0.82 | GRIN2B (0.57) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL4483176 | 0.81 | GRIN2B (0.56) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL16497829 | 0.80 | GRIN2B (0.53) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL1335289 | 0.80 | GRIN2B (0.56) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL15908894 | 0.80 | GRIN2B (0.56) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL65166 | 0.80 | GRIN2B (0.53) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL16495055 | 0.79 | GRIN2B (0.52) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL15909078 | 0.79 | GRIN2B (0.52) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL44500 | 0.79 | GRIN2B (0.52) | GRIN2BHCRTR1HCRTR2ACACBDPP4 | |
| SCHEMBL15918310 | 0.78 | GRIN2B (0.49) | GRIN2BHRH3CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |