Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25154755 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154467 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154405 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154325 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154386 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154747 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154347 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154479 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154640 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA | |
| SCHEMBL25154639 | 0.86 | ABCB1 (0.34) | SMN1; SMN2ABCB1TSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064768-A1 | G-PROTEIN-COUPLED RECEPTOR REGULATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-04-20 | — | — | WO | disclosed |