Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081822 | 0.84 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL25081778 | 0.76 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL21599313 | 0.76 | CYP2D6 (0.37) | CYP2D6 | |
| SCHEMBL25081757 | 0.75 | CYP2D6 (0.36) | CYP2D6KDM4EMAPT | |
| SCHEMBL22916025 | 0.73 | CYP2D6 (0.39) | CYP2D6KDM4EMAPT | |
| SCHEMBL25081710 | 0.72 | CYP2D6 (0.37) | CYP2D6 | |
| SCHEMBL8316424 | 0.71 | CYP2D6 (0.39) | CYP2D6KDM4EMAPT | |
| SCHEMBL25081798 | 0.71 | CYP2D6 (0.36) | CYP2D6 | |
| SCHEMBL22916049 | 0.70 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL13221871 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023063751-A1 | COMPOUNDS INHIBITING ALK AND/OR EGFR MUTATION KINASES AND MEDICAL USE THEREOF | 제이투에이치바이오텍 주식회사 | 2023-04-20 | — | — | WO | disclosed |