⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306260 | 1.00 | — | — | |
| SCHEMBL11404077 | 0.74 | — | — | |
| SCHEMBL1964304 | 0.72 | — | — | |
| SCHEMBL11618678 | 0.72 | — | — | |
| SCHEMBL2342556 | 0.72 | — | — | |
| SCHEMBL25324243 | 0.71 | CA1 (0.32) | — | |
| SCHEMBL2048729 | 0.71 | CA1 (0.32) | — | |
| SCHEMBL1062072 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL1243413 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL6897696 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345920-B1 | NOVEL SULFAMIDES AND THEIR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-04-12 | — | — | EP | claimed |
| JP-3350048-B2 | — | — | 2002-11-25 | — | — | JP | claimed |
| US-5593981-A | Method and treatment of androgen-related diseases | ENDORECHERCHE INC. (CA) | 1997-01-14 | — | — | US | claimed |
| US-5372996-A | Method of treatment of androgen-related diseases | ENDORECHERCHE, INC. (CA) | 1994-12-13 | — | — | US | claimed |
| US-5364847-A | Inhibitors of sex steroid biosynthesis and methods for their production and use | ENDORECHERCHE (CA) | 1994-11-15 | — | — | US | claimed |
| EP-0595796-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1994-05-11 | — | — | EP | claimed |
| EP-0485392-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1992-05-20 | — | — | EP | claimed |
| WO-1991000733-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | claimed |
| WO-1991000732-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | claimed |
| US-9586945-B2 | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-07 | — | — | US | disclosed |
| US-9365512-B2 | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9238619-B2 | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-01-19 | — | — | US | disclosed |
| US-9067871-B2 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9051280-B2 | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-09 | — | — | US | disclosed |
| EP-0595796-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1994-05-11 | — | — | EP | disclosed |
| EP-0485392-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462189-A1 | COMBINATION THERAPY FOR TREATMENT OF ESTROGEN SENSITIVE DISEASES. | ENDORECHERCHE INC (CA) | 1991-12-27 | — | — | EP | disclosed |
| WO-1991000733-A1 | METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | disclosed |
| WO-1991000732-A1 | ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY | ENDORECHERCHE INC. (CA) | 1991-01-24 | — | — | WO | disclosed |
| WO-1990010462-A1 | COMBINATION THERAPY FOR TREATMENT OF ESTROGEN SENSITIVE DISEASES | ENDORECHERCHE INC. (CA) | 1990-09-20 | — | — | WO | disclosed |