Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25161315 | 0.90 | HDAC1 (0.51) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161760 | 0.88 | HDAC1 (0.47) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161006 | 0.86 | HDAC2 (0.50) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161008 | 0.86 | HDAC1 (0.51) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161001 | 0.86 | HDAC2 (0.49) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161231 | 0.85 | HDAC2 (0.58) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161266 | 0.84 | HDAC1 (0.58) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL23517747 | 0.84 | SMN1; SMN2 (0.54) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161862 | 0.82 | HDAC2 (0.46) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL25161000 | 0.82 | HDAC1 (0.50) | HDAC2KCNH2CYP1A2CYP2C18CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119479-A1 | A HISTONE DEACETYLASE INHIBITOR HAVING A NITROGEN-CONTAINING AROMATIC HETEROCYCLYL GROUP | SHIONOGI & CO., LTD. (JP) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230119479-A1 | A HISTONE DEACETYLASE INHIBITOR HAVING A NITROGEN-CONTAINING AROMATIC HETEROCYCLYL GROUP | HDAC2, HDAC1, HDAC11 | HDAC2 1/4885KCNH2 1618/4885CYP1A2 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.