Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 18/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329320 | 0.87 | HCRTR2 (0.38) | HCRTR2HCRTR1 | |
| SCHEMBL25164317 | 0.87 | HCRTR2 (0.38) | HCRTR2HCRTR1 | |
| SCHEMBL30328835 | 0.87 | HCRTR2 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL25164755 | 0.87 | HCRTR2 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL25164772 | 0.86 | CYP11B1 (0.32) | — | |
| SCHEMBL30328712 | 0.85 | HCRTR2 (0.36) | HCRTR2HCRTR1 | |
| SCHEMBL25164413 | 0.85 | HCRTR2 (0.36) | HCRTR2HCRTR1 | |
| SCHEMBL25164868 | 0.85 | HCRTR2 (0.38) | HCRTR2HCRTR1 | |
| SCHEMBL25163674 | 0.83 | CNR2 (0.31) | — | |
| SCHEMBL30328728 | 0.83 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |