Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.58 |
| ▸ | EHMT1 | Q9H9B1 | 11/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329764 | 1.00 | EHMT2 (0.58) | EHMT2EHMT1PIK3CDCSF1RCDK4 | |
| SCHEMBL30330189 | 0.85 | EHMT2 (0.62) | EHMT2EHMT1IGF1R | |
| SCHEMBL25166182 | 0.85 | EHMT2 (0.62) | EHMT2EHMT1IGF1R | |
| SCHEMBL30329734 | 0.84 | EHMT2 (0.47) | EHMT2EHMT1IGF1R | |
| SCHEMBL25165994 | 0.84 | EHMT2 (0.47) | EHMT2EHMT1IGF1R | |
| SCHEMBL25166242 | 0.84 | EHMT2 (0.56) | EHMT2EHMT1IGF1R | |
| SCHEMBL25166056 | 0.84 | EHMT2 (0.47) | EHMT2EHMT1IGF1R | |
| SCHEMBL30329753 | 0.84 | EHMT2 (0.56) | EHMT2EHMT1IGF1R | |
| SCHEMBL30330089 | 0.81 | IGF1R (0.51) | EHMT2EHMT1IGF1R | |
| SCHEMBL30330166 | 0.81 | IGF1R (0.51) | EHMT2EHMT1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |