Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 9/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166069 | 1.00 | EHMT2 (0.38) | EHMT2EHMT1 | |
| SCHEMBL30329862 | 1.00 | EHMT2 (0.38) | EHMT2EHMT1 | |
| SCHEMBL25166350 | 1.00 | EHMT2 (0.38) | EHMT2EHMT1 | |
| SCHEMBL25165951 | 1.00 | EHMT2 (0.38) | EHMT2EHMT1 | |
| SCHEMBL30329751 | 1.00 | EHMT2 (0.38) | EHMT2EHMT1 | |
| SCHEMBL25166385 | 0.85 | EHMT2 (0.53) | EHMT2EHMT1 | |
| SCHEMBL25165953 | 0.85 | EHMT2 (0.37) | EHMT2EHMT1 | |
| SCHEMBL25165964 | 0.85 | EHMT2 (0.37) | EHMT2EHMT1 | |
| SCHEMBL25166316 | 0.85 | EHMT2 (0.37) | EHMT2EHMT1 | |
| SCHEMBL25165904 | 0.85 | EHMT2 (0.37) | EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |