SCHEMBL25166241

SCHEMBL25166241

CNc1cc(C)nc(Nc2cc3c(c(C4=CCNCCC4)c2F)OCC[C@@H]3C)n1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EHMT2 Q96KQ7 12/20 0.49
▸ EHMT1 Q9H9B1 12/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25166118 1.00 EHMT2 (0.49) EHMT2EHMT1
SCHEMBL30329899 1.00 EHMT2 (0.49) EHMT2EHMT1
SCHEMBL31107901 1.00 EHMT2 (0.49) EHMT2EHMT1
SCHEMBL30329904 0.92 EHMT2 (0.53) EHMT2EHMT1
SCHEMBL25166336 0.92 EHMT2 (0.53) EHMT2EHMT1
SCHEMBL25166385 0.92 EHMT2 (0.53) EHMT2EHMT1
SCHEMBL30329780 0.85 EHMT2 (0.53) EHMT2EHMT1
SCHEMBL25166092 0.85 EHMT2 (0.53) EHMT2EHMT1
SCHEMBL25166260 0.85 EHMT2 (0.52) EHMT2EHMT1
SCHEMBL30329718 0.85 EHMT2 (0.52) EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064586-A1 NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF TANGO THERAPEUTICS, INC. (US) 2023-04-20 — — WO disclosed
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