Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 17/20 | 0.65 |
| ▸ | EHMT1 | Q9H9B1 | 17/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329738 | 1.00 | EHMT2 (0.65) | EHMT2EHMT1JAK2JAK3PTK2 | |
| SCHEMBL30330204 | 0.84 | EHMT2 (0.68) | EHMT2EHMT1 | |
| SCHEMBL25166159 | 0.84 | EHMT2 (0.68) | EHMT2EHMT1 | |
| SCHEMBL25166432 | 0.84 | EHMT2 (0.68) | EHMT2EHMT1 | |
| SCHEMBL25166023 | 0.83 | EHMT2 (0.62) | EHMT2EHMT1IGF1R | |
| SCHEMBL30329826 | 0.83 | EHMT2 (0.62) | EHMT2EHMT1IGF1R | |
| SCHEMBL25166510 | 0.83 | EHMT2 (0.47) | EHMT2EHMT1 | |
| SCHEMBL30329825 | 0.81 | EHMT2 (0.68) | EHMT2EHMT1IGF1R | |
| SCHEMBL25166163 | 0.81 | EHMT2 (0.68) | EHMT2EHMT1IGF1R | |
| SCHEMBL30329815 | 0.81 | EHMT2 (0.68) | EHMT2EHMT1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |