Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 9/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA4 | P22748 | 7/20 | 0.43 |
| ▸ | CA5A | P35218 | 7/20 | 0.43 |
| ▸ | CA7 | P43166 | 7/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.43 |
| ▸ | CA6 | P23280 | 4/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713931 | 1.00 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL25440550 | 1.00 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL21022679 | 1.00 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL25166723 | 1.00 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL3787332 | 0.89 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL14247838 | 0.89 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL14782693 | 0.89 | TSHR (0.63) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL25171315 | 0.88 | TSHR (0.62) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL21022864 | 0.88 | TSHR (0.62) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL1713321 | 0.88 | TSHR (0.62) | TSHRPTPN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862003-B1 | AN SGLT-2 INHIBITOR FOR USE IN THE TREATMENT OF A METABOLIC DISORDER IN FELINE ANIMALS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-10-25 | — | — | EP | disclosed |
| EP-3485890-B1 | SGLT2 INHIBITORS FOR TREATMENT OF METABOLIC DISORDERS IN CANINE ANIMALS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-10 | — | — | EP | disclosed |