Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 17/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124800 | 0.94 | TTK (0.43) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22124680 | 0.94 | TTK (0.45) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22125103 | 0.93 | TTK (0.45) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22124762 | 0.93 | TTK (0.45) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22125197 | 0.93 | TTK (0.45) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22139173 | 0.92 | TTK (0.44) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22124779 | 0.92 | TTK (0.44) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22124901 | 0.92 | TTK (0.44) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL30172056 | 0.92 | TTK (0.44) | TTKBRAFPTK6MAPKAPK5 | |
| SCHEMBL22123517 | 0.92 | TTK (0.45) | TTKBRAFPTK6MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | claimed |