SCHEMBL25171

SCHEMBL25171

C[Si](C)(C)CC[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066602 0.77
SCHEMBL27842292 0.74
SCHEMBL3300416 0.71
SCHEMBL1042736 0.67
SCHEMBL3627555 0.67
SCHEMBL3215340 0.65
SCHEMBL7056812 0.65
SCHEMBL15264164 0.64
Lithium Ion SCHEMBL12482702 0.64
SCHEMBL3915910 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024060356-A1 ECONOMICAL AND FEASIBLE METHOD FOR INDUSTRIALLY PRODUCING DEUTERATED COVID-19 MEDICAMENT KEY INTERMEDIATE 广州谷森制药有限公司 2024-03-28 WO claimed
WO-2024027370-A1 NITROGEN-CONTAINING FUSED THREE RING PRMT5 INHIBITOR, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 上海和誉生物医药科技有限公司 2024-02-08 WO claimed
WO-2023137876-A1 METHOD FOR PREPARING INTERMEDIATE FOR SYNTHESIZING NEW DEUTERATED CYANO COMPOUND 广州谷森制药有限公司 2023-07-27 WO claimed
CN-116332819-A Economical and feasible method for industrially producing key intermediate of deuterated drug 广州谷森制药有限公司 2023-06-27 CN claimed
CN-115485259-A Substituted hydroxystilbene compounds and derivatives, synthesis and use thereof 凯楠公爵IP有限责任公司 2022-12-16 CN claimed
CN-114956934-A Preparation method of intermediate for synthesizing novel deuterated cyano compound 广州谷森制药有限公司 2022-08-30 CN claimed
CN-110054616-B Preparation method of triazine IDH inhibitor 南京圣和药业股份有限公司 2021-11-23 CN claimed
EP-3495359-A1 FLAP MODULATORS Janssen Pharmaceutica NV (BE) 2019-06-12 EP claimed
US-10259806-B2 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2 pyridyl]amino]pyrazine-2-carbonitrile and therapeutic uses thereof CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2019-04-16 US claimed
EP-3070085-B1 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-01-09 EP claimed
WO-1993001179-A1 PROCESS FOR THE PREPARATION OF BACCATIN III AND 10-DEACETYL BACCATIN III DERIVATIVES RHONE-POULENC RORER S.A. (FR) 1993-01-21 WO claimed
EP-0522958-A1 Process for the preparation of Bacchatin III and of 10 desacetyl-Bacchatin III derivatives Aventis Pharma S.A. (FR) 1993-01-13 EP claimed
US-5075476-A Reacting alkylthiophenyl carbonates with dialkyl sulfates in presence of carbonates, bicarbonates, oxides or hydroxides of group I or II metals MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-12-24 US claimed
WO-1991017976-A1 PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES RHONE-POULENC RORER S.A. (FR) 1991-11-28 WO claimed
EP-0414610-A1 Process for the enantioselective preparation of phenylisoserine derivatives CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1991-02-27 EP claimed
EP-0401696-A2 Process for production of sulfonium compounds and novel methylthiophenyl derivatives MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-12-12 EP claimed
EP-0336840-A1 Process for the preparation of taxol CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-10-11 EP claimed
EP-0336841-A1 Process for the preparation of baccatin III derivatives and of desacetyl-10 baccatin III RHONE-POULENC SANTE (FR) 1989-10-11 EP claimed
EP-0325130-A2 Substituted pyridines BAYER AG (DE) 1989-07-26 EP claimed
EP-0258184-A2 Quinoline derivatives as herbicide antagonists for cultivated plants CIBA-GEIGY AG (CH) 1988-03-02 EP claimed