Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112621 | 0.97 | PTK6 (0.33) | PTK6TTKTBK1 | |
| Formic Acid SCHEMBL25173464 | 0.92 | PTK2 (0.34) | PTK6TTK | |
| SCHEMBL32675701 | 0.90 | PTK6 (0.32) | PTK6TTK | |
| SCHEMBL24112318 | 0.90 | PTK6 (0.32) | PTK6TTK | |
| SCHEMBL24112441 | 0.90 | PTK2 (0.36) | PTK6TTK | |
| Formic Acid SCHEMBL30171877 | 0.89 | PTK6 (0.37) | PTK6TTKTBK1 | |
| SCHEMBL22124404 | 0.89 | PTK6 (0.39) | PTK6TTKTBK1 | |
| Hydrochloric Acid SCHEMBL25170428 | 0.89 | PTK6 (0.39) | PTK6TTKTBK1 | |
| Formic Acid SCHEMBL30171731 | 0.89 | PTK6 (0.34) | PTK6TTKTBK1 | |
| SCHEMBL22123091 | 0.88 | PTK6 (0.35) | PTK6TTKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | IKZF3, RRP15, IK | PTK6 925/4885TTK 4336/4885TBK1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.