Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14300742 | 0.79 | FFAR4 (0.37) | FFAR4 | |
| SCHEMBL1410200 | 0.70 | DPP4 (0.45) | FFAR4 | |
| SCHEMBL1410108 | 0.70 | FFAR4 (0.37) | AKR1C3AKR1C2FFAR4 | |
| SCHEMBL1410243 | 0.63 | NOTUM (0.57) | — | |
| SCHEMBL1410358 | 0.60 | FFAR4 (0.48) | FFAR4 | |
| SCHEMBL8692384 | 0.58 | AKR1C3 (0.63) | AKR1C3AKR1C2 | |
| SCHEMBL6549986 | 0.57 | PPARG (0.53) | — | |
| Hydrochloric Acid SCHEMBL6548048 | 0.56 | PPARG (0.52) | — | |
| SCHEMBL1295801 | 0.55 | AKR1C3 (0.40) | AKR1C3AKR1C2 | |
| SCHEMBL10936223 | 0.55 | SMN1; SMN2 (0.54) | AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | NES, BMI1, DOT1L | AKR1C3 1630/4885AKR1C2 1043/4885FFAR4 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.