SCHEMBL25181753

SCHEMBL25181753

O=C(C1=NCCO1)C1=NCCO1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
NFKB1 P19838 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29287902 0.97 HDAC3 (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10349144 0.84 HDAC3 (0.38) HDAC3HDAC4HDAC1HDAC7HDAC2
Glutaral SCHEMBL28266755 0.82 HIF1A (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1030035 0.82
SCHEMBL10627947 0.81 HDAC3 (0.43) HDAC3HDAC4HDAC1HDAC7HDAC2
Glycidol SCHEMBL28870162 0.81 HDAC3 (0.32) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1060745 0.80
SCHEMBL13154302 0.80
SCHEMBL28834436 0.80
SCHEMBL1060747 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023206126-A1 USE OF PROTOPORPHYRINOGEN OXIDASE 北京大北农生物技术有限公司 2023-11-02 WO claimed
WO-2023077262-A1 PESTICIDE MICROGRANULE FOR AERIAL FOLIAR SPRAYING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 中国农业科学院植物保护研究所 2023-05-11 WO claimed
WO-2022237541-A1 USE OF PROTOPORPHYRINOGEN OXIDASE 北京大北农生物技术有限公司 2022-11-17 WO claimed
CN-107556261-B Containing CF22-oxazolinone compounds and preparation method thereof 四川大学 2021-03-02 CN claimed
CN-107167472-B The rapid assay methods of total cyanide in a kind of ore pulp containing cyanogen 长春黄金研究院 2019-12-03 CN claimed
CN-110511328-A A kind of branch point breaking type hyperbranched resin and the preparation method and application thereof UNIV SOUTH CHINA TECH 2019-11-29 CN claimed
CN-106414555-B Thermoplastic compositions made from polyamide polymers obtained from a prepolymer and a chain extender and methods of making 阿科玛法国公司 2019-10-11 CN claimed
CN-108101904-B A method of preparing quinoquinazolone derivative 苏州大学张家港工业技术研究院 2019-08-30 CN claimed
CN-106946700-B The synthetic method and its application of tea caterpillar sex pheromone 西北农林科技大学 2019-06-07 CN claimed
CN-109824740-A The method mutually converted between the different pyrazolone reagent derivatives of reducing sugar 西北大学 2019-05-31 CN claimed
CN-105943557-A Anti-rheumatic-arthritis emulsifiable paste composition and preparation method thereof 内蒙古农业大学 2016-09-21 CN claimed
CN-105766993-A Compounded sustained-release sterilizing material 中化化工科学技术研究总院 2016-07-20 CN claimed
CN-102000487-B Method for capturing carbon dioxide UNIV SHANGHAI MARITIME 2012-09-05 CN claimed
CN-102197031-A Substituted 5-aminopyrazoles and use thereof BAYER SCHERING PHARMA AG 2011-09-21 CN claimed
CN-102000487-A Method for capturing carbon dioxide UNIV SHANGHAI MARITIME 2011-04-06 CN claimed
CN-102002011-A Method for preparing 2-oxazolinone UNIV SHANGHAI MARITIME 2011-04-06 CN claimed
CN-101157613-B Variegata snellen sex pheromone and method for synthesizing same UNIV FUDAN 2011-03-23 CN claimed
CN-101222950-A Processes for production of 4-(biphenylyl)azetidin-2-one phosphonic acids MICROBIA INC (US) 2008-07-16 CN claimed
CN-101218213-A Process for preparing phenolic 4-biphenylylazetidin-2-ones MICROBIA INC (US) 2008-07-09 CN claimed
CN-101213170-A Process for production of 4-biphenylylazetidin-2-ones MICROBIA INC (US) 2008-07-02 CN claimed