Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25171242 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL1906182 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL10704417 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL25178882 | 0.98 | TSHR (0.56) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL25171273 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL1906318 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL25172421 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL2842318 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL9718888 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 | |
| SCHEMBL25178111 | 0.96 | TSHR (0.67) | TSHRALDH1A1LMNATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023085299-A1 | CATIONIC LIPID | 武田薬品工業株式会社 | 2023-05-19 | — | — | WO | disclosed |