SCHEMBL25181783

SCHEMBL25181783

C=CCCCC(CCC)CCCCC

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ALDH1A1 P00352 4/20 0.54
LMNA P02545 1/20 0.41
OPRM1 P35372 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25185574 0.98 TSHR (0.60) TSHRALDH1A1LMNAOPRM1PLA2G2C
SCHEMBL9718866 0.98 TSHR (0.60) TSHRALDH1A1LMNAOPRM1PLA2G2C
SCHEMBL25172371 0.96 TSHR (0.62) TSHRALDH1A1LMNAOPRM1PLA2G2C
SCHEMBL25178137 0.96 TSHR (0.61) TSHRALDH1A1LMNAOPRM1PLA2G2C
SCHEMBL28049542 0.94 TSHR (0.67) TSHRALDH1A1LMNAPLA2G2CCYP3A4
SCHEMBL9718834 0.94 TSHR (0.67) TSHRALDH1A1LMNAPLA2G2CCYP3A4
SCHEMBL28049541 0.94 TSHR (0.67) TSHRALDH1A1LMNAPLA2G2CCYP3A4
SCHEMBL25178897 0.94 TSHR (0.67) TSHRALDH1A1LMNAPLA2G2CCYP3A4
SCHEMBL25178895 0.94 TSHR (0.67) TSHRALDH1A1LMNAPLA2G2CCYP3A4
SCHEMBL25178120 0.93 TSHR (0.58) TSHRALDH1A1LMNAOPRM1PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed