Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956897 | 1.00 | BCL2 (0.78) | BCL2 | |
| SCHEMBL1956783 | 0.94 | BCL2 (0.78) | BCL2 | |
| SCHEMBL1956598 | 0.92 | BCL2 (0.78) | BCL2 | |
| SCHEMBL19425178 | 0.89 | BCL2 (0.62) | BCL2 | |
| SCHEMBL1956916 | 0.88 | BCL2 (0.77) | BCL2 | |
| SCHEMBL1954390 | 0.87 | — | — | |
| SCHEMBL30467957 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1861473 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1702329 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1956575 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376480-A2 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |