Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25185190 | 1.00 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25564815 | 0.86 | CSF1R (0.82) | CSF1R | |
| SCHEMBL25564654 | 0.85 | CSF1R (0.79) | CSF1R | |
| SCHEMBL29213100 | 0.85 | CSF1R (0.79) | CSF1R | |
| SCHEMBL25263977 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25181745 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25565216 | 0.85 | CSF1R (0.88) | CSF1R | |
| SCHEMBL25185186 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25185187 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25171428 | 0.84 | CSF1R (1.00) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | claimed |
| CN-113999221-A | 6-substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2022-02-01 | — | — | CN | claimed |
| CN-113999221-B | 6-substituted indolone derivative and medical application thereof | 南京中医药大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |
| CN-113999221-A | 6-substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2022-02-01 | — | — | CN | disclosed |