SCHEMBL2518756

SCHEMBL2518756

[CH2]CC(C#N)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68459 0.81
SCHEMBL7037006 0.78
SCHEMBL11508783 0.73
SCHEMBL4521389 0.72
SCHEMBL2537848 0.71
SCHEMBL31063929 0.71
SCHEMBL14546289 0.71
SCHEMBL214487 0.71
SCHEMBL16508635 0.70
SCHEMBL29154614 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034810-B2 Matrix metalloproteinase inhibitors; antiinflammatory agengs; rheumatoid arthritis, osteoarthritis; antitumor, anticarcinogenic, and antimetastasis agents; respiratory system disorders, chronic obstructive pulmonary disease, deblocking, deprotecting NOVARTIS AG (CH) 2011-10-11 US disclosed
CN-101010290-B Diimmonium compound and use thereof NIPPON KAYAKU KK 2011-08-03 CN disclosed
EP-2085379-A1 Arylsulfonamido-substituted hydroxamic acid derivatives Novartis AG (CH) 2009-08-05 EP disclosed
US-7521006-B2 Diimmonium compound and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-21 US disclosed
US-20080275127-A1 Arylsulfonamido-substituted hydroxamic acid derivatives BREITENSTEIN WERNER 2008-11-06 US disclosed
CN-100430374-C Diimonium salt compound and use thereof NIPPON KAYAKU KK (JP) 2008-11-05 CN disclosed
US-20080067478-A1 Quaternary salt of N,N,N',N'-tetrakis(p-aminophenyl)phenylene diimmonium compound; stability; heat and light resistance; near-infrared aborbing filters, optical recording media and filters, plasma display panels NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-03-20 US disclosed
CN-101010290-A Diimmonium compound and use thereof NIPPON KAYAKU KK (JP) 2007-08-01 CN disclosed
EP-1787978-A1 DIIMMONIUM COMPOUND AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2007-05-23 EP disclosed
CN-1878747-A Diimonium salt compound and use thereof NIPPON KAYAKU KK (JP) 2006-12-13 CN disclosed
US-7138432-B1 Arylsulfonamido-substituted hydroxamic acid derivatives NOVARTIS AG (CH) 2006-11-21 US disclosed
EP-1683784-A1 DIIMONIUM SALT COMPOUND AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2006-07-26 EP disclosed
CN-1215055-C Arylsulfonylamino-substituted hydroxamic acid derivatives NOVARTIS AG (CH) 2005-08-17 CN disclosed
US-20050148786-A1 Diimmonium compound and use thereof NIPPON KAYAKU KABUSHIKI KAISHA 2005-07-07 US disclosed
CN-1368958-A Arylsulfonamido-substituted hydroxamic acid derivatives NOVARTIS AG (CH) 2002-09-11 CN disclosed
EP-1202961-A1 ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES Novartis AG (CH) 2002-05-08 EP disclosed
WO-2001010827-A1 ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES NOVARTIS AG (CH) 2001-02-15 WO disclosed